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Synthesis of 3-aroylimidazo[1,2-a]pyridines via CuCl2 catalyzed tandem dual carbon–nitrogen bonding

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dc.contributor.author Kumar, Anil
dc.date.accessioned 2021-10-17T13:57:27Z
dc.date.available 2021-10-17T13:57:27Z
dc.date.issued 2014
dc.identifier.uri https://www.infona.pl/resource/bwmeta1.element.elsevier-7afea7e7-18aa-370f-ba08-a4b5ea4fb1d3
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2872
dc.description.abstract A novel tandem approach has been demonstrated for the direct synthesis of bioactive 3-aroylimidazo[1,2-a]pyridines from chalcones and 2-aminopyridines. The reported tandem reaction is atom-economical and expected to proceed via 1,4-Michael addition followed by copper catalyzed oxidative C–N bonding. Catalytic amount of copper was found to be crucial for the success of tandem reaction and it altered the reaction pathway to furnish entirely new products. This protocol proved to be convenient as reaction proceeds smoothly without the necessity of any ligand in the presence of air as oxidant. en_US
dc.language.iso en en_US
dc.publisher INFOFNA en_US
dc.subject Chemistry en_US
dc.subject Tandem reaction en_US
dc.subject Dual C–N bonding en_US
dc.subject 3-Aroylimidazo[1,2-a]pyridines en_US
dc.subject Chalcone en_US
dc.title Synthesis of 3-aroylimidazo[1,2-a]pyridines via CuCl2 catalyzed tandem dual carbon–nitrogen bonding en_US
dc.type Article en_US


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