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Copper catalyzed tandem oxidative C–H amination/cyclizations: Direct access to imidazo[1,2-a]pyridines

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dc.contributor.author Khungar, Bharti
dc.contributor.author Kumar, Anil
dc.date.accessioned 2021-10-27T04:13:03Z
dc.date.available 2021-10-27T04:13:03Z
dc.date.issued 2013
dc.identifier.uri https://pubs.rsc.org/en/content/articlelanding/2013/RA/C3RA43889A
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2977
dc.description.abstract A simple and convenient strategy is described for the synthesis of imidazo[1,2-a]pyridines via inexpensive copper-catalyzed tandem imine formation and intramolecular aerobic oxidative C–H bond amination/cyclizations. An array of imidazo[1,2-a]pyridines were prepared by the reaction of readily available acetophenones and 2-aminopyridines in good to excellent yields (48–92%). The scope of the method was validated by a single step synthesis of Zolimidine, a drug used for peptic ulcers, in 61% yield. en_US
dc.language.iso en en_US
dc.publisher RSC en_US
dc.subject Chemistry en_US
dc.subject Copper-Catalyzed en_US
dc.subject C–H amination/cyclizations en_US
dc.subject Imidazo[1,2-a]pyridines en_US
dc.title Copper catalyzed tandem oxidative C–H amination/cyclizations: Direct access to imidazo[1,2-a]pyridines en_US
dc.type Article en_US


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