| dc.contributor.author | Kumar, Dalip | |
| dc.date.accessioned | 2021-10-27T04:20:54Z | |
| dc.date.available | 2021-10-27T04:20:54Z | |
| dc.date.issued | 2011-10 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0960894X11010353?via%3Dihub | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3052 | |
| dc.description.abstract | A series of 3,5-bis(indolyl)-1,2,4-thiadiazoles were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of indole-3-thiocarboxamide 3 with iodobenzene diacetate underwent oxidative dimerization to give 3,5-bis(indolyl)-1,2,4-thiadiazoles 4a–n. Among the synthesized bis(indoly)-1,2,4-thiadiazoles, the compound 4h with 4-chlorobenzyl and methoxy substituents showed the most potent activity. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsiever | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Bisindoles | en_US |
| dc.subject | 1,2,4-Thiadiazoles | en_US |
| dc.subject | Anticancer agents | en_US |
| dc.subject | Dimerization | en_US |
| dc.subject | Hypervalent iodine regents | en_US |
| dc.title | Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4-thiadiazoles | en_US |
| dc.type | Article | en_US |
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