| dc.contributor.author | Kumar, Dalip | |
| dc.date.accessioned | 2021-10-27T04:21:51Z | |
| dc.date.available | 2021-10-27T04:21:51Z | |
| dc.date.issued | 2009-05 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0040403909003670?via%3Dihub | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3068 | |
| dc.description.abstract | The reaction of α-tosyloxy ketones, sodium azide, and terminal alkynes in presence of copper(I) in aqueous polyethylene glycol afforded regioselectively 1,4-disubstituted 1,2,3-triazoles in good yield at ambient temperature. The one-pot exclusive formation of 1,4-disubstituted 1,2,3-triazoles involves in situ formation of α-azido ketones, followed by cycloaddition reaction with terminal alkyne. The generality of this one-pot method was demonstrated by synthesizing an array of diverse 1,4-disubstituted 1,2,3-triazoles. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsiever | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | α-Tosyloxy ketones | en_US |
| dc.subject | 1,4-Disubstituted-1,2,3-triazoles | en_US |
| dc.subject | click chemistry | en_US |
| dc.subject | Nitrogen heterocycles | en_US |
| dc.subject | Copper iodide | en_US |
| dc.title | A facile and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles using click chemistry | en_US |
| dc.type | Article | en_US |
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||