Microwave assisted aminocatalyzed [3 + 2] annulation between α-iminonitriles and succinaldehyde: synthesis of pyrrole-3-methanols and related polycyclic ring systems

Kumar, Indresh

dc.contributor.author	Kumar, Indresh
dc.date.accessioned	2021-10-27T04:27:43Z
dc.date.available	2021-10-27T04:27:43Z
dc.date.issued	2016
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra06831f
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3169
dc.description.abstract	A quick and highly efficient method for the synthesis of substituted pyrrole-3-methanols from α-iminonitriles and succinaldehyde under microwave irradiation is reported. This one-pot method involves aminocatalyzed direct Mannich reaction-cyclization-dehydrocyanation followed by NaBH4 reduction sequence in good yields (up to 75%). Further applications of this method are demonstrated through the rapid synthesis of polycyclic heterocycles such as pyrrolo-dihydrochromene and pyrrolo-dihydroquinoline compounds.	en_US
dc.language.iso	en	en_US
dc.publisher	RSC	en_US
dc.subject	Chemistry	en_US
dc.subject	Microwave	en_US
dc.subject	Aminocatalyzed [3 + 2]	en_US
dc.subject	Pyrrole-3-methanols	en_US
dc.title	Microwave assisted aminocatalyzed [3 + 2] annulation between α-iminonitriles and succinaldehyde: synthesis of pyrrole-3-methanols and related polycyclic ring systems	en_US
dc.type	Article	en_US