| dc.contributor.author | Kumar, Indresh | |
| dc.date.accessioned | 2021-10-27T04:27:59Z | |
| dc.date.available | 2021-10-27T04:27:59Z | |
| dc.date.issued | 2013 | |
| dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc42431f | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3175 | |
| dc.description.abstract | A new method for one-pot synthesis of 2,3-substituted piperidine from N-PMP aldimine and aqueous glutaraldehyde via formal [4+2] cycloaddition is reported. This reaction involves organocatalytic direct Mannich reaction–reductive cyclization with high yields (up to 90%) and excellent enantioselectivities (up to >99%). The practicability of this method is also shown at a gram scale as well as through the synthesis of functionalized (−)-anabasine | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | RSC | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Enantioselective [4+2] | en_US |
| dc.subject | Organocatalytic | en_US |
| dc.title | Highly enantioselective [4+2] annulation via organocatalytic Mannich-reductive cyclization: one-pot synthesis of functionalized piperidines | en_US |
| dc.type | Article | en_US |
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