| dc.contributor.author |
Sakhuja, Rajeev |
|
| dc.date.accessioned |
2021-11-11T10:57:40Z |
|
| dc.date.available |
2021-11-11T10:57:40Z |
|
| dc.date.issued |
2021-08 |
|
| dc.identifier.uri |
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajoc.202100384 |
|
| dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3338 |
|
| dc.description.abstract |
A one-pot spirocyclization of 2-aryl-2,3-dihydrophthalazine-1,4-diones with maleimides was achieved via RhIII-catalyzed sequential ortho-alkenylation followed by intramolecular aza-Michael-type addition/protonation process. The featured strategy furnishes a series of diversely decorated spiro[indazolo[1,2-b]phthalazine-13,3′-pyrrolidine]-2′,5′,6,11-tetraones in high yields from a variety of 2-aryl-2,3-dihydrophthalazine-1,4-diones and N-aryl/alkyl maleimides, which can be scaled-up easily. Isolation and characterization of a maleimide-coordinated five-membered rhodacyclic intermediate provided a strong evidence for the proposed mechanism of the reaction. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Wiley |
en_US |
| dc.subject |
Chemistry |
en_US |
| dc.subject |
Rhodium-Catalyzed |
en_US |
| dc.subject |
Spirocyclization of Maleimide |
en_US |
| dc.subject |
Pentacyclic Spiro-Succinimides |
en_US |
| dc.title |
Rhodium-Catalyzed Spirocyclization of Maleimide with N-Aryl-2,3-dihydrophthalazine-1,4-dione to Access Pentacyclic Spiro-Succinimides |
en_US |
| dc.type |
Article |
en_US |