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Fluorescent glutamine and asparagine as promising probes for chemical biology

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dc.contributor.author Sakhuja, Rajeev
dc.contributor.author Jha, Prabhat Nath
dc.contributor.author Kumar, Dalip
dc.date.accessioned 2021-11-11T10:57:49Z
dc.date.available 2021-11-11T10:57:49Z
dc.date.issued 2021
dc.identifier.uri https://pubs.rsc.org/en/content/articlelanding/2021/ob/d1ob01029h
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3340
dc.description.abstract Fluorescent probes have become valuable tools in chemical biology, providing interesting inferences for unfolding the complexities of natural biochemical processes. In this study, we report the synthesis and characterization of fluorescent labelled glutamine (Gln) and asparagine (Asn) derivatives via traceless Staudinger ligation, which exhibited high fluorescence quantum yields, excellent photostabilities and emission of blue fluorescence in the visible region. The successful permeation of these fluorescent amino acids into cellular components proved their potential as fluorescent probes for chemical biology. en_US
dc.language.iso en en_US
dc.publisher RSC en_US
dc.subject Chemistry en_US
dc.subject Fluorescent en_US
dc.subject Glutamine en_US
dc.subject Asparagine en_US
dc.title Fluorescent glutamine and asparagine as promising probes for chemical biology en_US
dc.type Article en_US


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