dc.contributor.author |
Sakhuja, Rajeev |
|
dc.date.accessioned |
2021-11-11T10:58:46Z |
|
dc.date.available |
2021-11-11T10:58:46Z |
|
dc.date.issued |
2018 |
|
dc.identifier.uri |
https://pubs.rsc.org/en/content/articlelanding/2018/ob/c8ob00586a |
|
dc.identifier.uri |
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3354 |
|
dc.description.abstract |
An efficient, one-pot Cu-catalyzed tandem synthesis of fluorescent 1-benzyl-2-phenyl-1,2-dihydro-5H-chromeno[4,3-d]pyrimidin-5-ones from 4-chloro-3-formylcoumarin and benzylamines was developed by in situ intramolecular cross-dehydrogenative C(sp3)–N bond formation in moderate-to-good yields under ligand-free ambient conditions. This synthesis was easily scalable, and the generality of the substrates was established. These coumarin-fused pyrimidines exhibited interesting photo-physical properties and high quantum yields, and would be potential candidates for facilitating suitable studies in medicinal chemistry and materials science. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
RSC |
en_US |
dc.subject |
Chemistry |
en_US |
dc.subject |
Synthesis |
en_US |
dc.subject |
Fluorescent coumarin-fused |
en_US |
dc.subject |
Pyrimidines via copper-catalyzed |
en_US |
dc.title |
An unprecedented tandem synthesis of fluorescent coumarin-fused pyrimidines via copper-catalyzed cross-dehydrogenative C(sp3)–N bond coupling |
en_US |
dc.type |
Article |
en_US |