| dc.description.abstract |
Some new 3-(2'-substitutedaryl -2',3'-dihydro-1 ',5'-benzothia/oxazepin-4'-yl)indoles 3a-h, 3-(2'-substitutedary 1-3'substitutedarylaminomethylene-2' ,3'-dihydro-1',5'-benzothia/oxazepin-4'-yl)indoles 4a-p and 3-(2'-substitutedary 1-3'substitutedarylazo- 2',3'- dihydro-1',5'- benzothia/oxazepin-4'-yl)indoles 5a-p have been synthesized and evaluated for antipsychotic activity. 3-[2'-( 4"-N,N-dimethylphenyl)-3' -arylaminomethylene-2',3'-dihydro-1 ,5-benzothiazepin-4'-yl] indole 4i showes most promising antipsychotic activity. The structures of all the compounds were determined by IR,1H NMR and mass spectrometry. |
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