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Detecting SARS-CoV-2 RNA prone clusters in a municipal wastewater network using fuzzy-Bayesian optimization model to facilitate wastewater-based epidemiology

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dc.contributor.author Srinivas, Rallapalli
dc.contributor.author Singh, Ajit Pratap
dc.date.accessioned 2022-12-21T09:28:47Z
dc.date.available 2022-12-21T09:28:47Z
dc.date.issued 2021-07
dc.identifier.uri https://www.sciencedirect.com/science/article/pii/S0048969721013620?via%3Dihub
dc.identifier.uri http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/8009
dc.description.abstract The current pandemic disease coronavirus (COVID-19) has not only become a worldwide health emergency, but also devoured the global economy. Despite appreciable research, identification of targeted populations for testing and tracking the spread of COVID-19 at a larger scale is an intimidating challenge. There is a need to quickly identify the infected individual or community to check the spread. The diagnostic testing done at large-scale for individuals has limitations as it cannot provide information at a swift pace in large populations, which is pivotal to contain the spread at the early stage of its breakouts. Recently, scientists are exploring the presence of SARS-CoV-2 RNA in the faeces discharged in municipal wastewater. Wastewater sampling could be a potential tool to expedite the early identification of infected communities by detecting the biomarkers from the virus. However, it needs a targeted approach to choose optimized locations for wastewater sampling. The present study proposes a novel fuzzy based Bayesian model to identify targeted populations and optimized locations with a maximum probability of detecting SARS-CoV-2 RNA in wastewater networks. Consequently, real time monitoring of SARS-CoV-2 RNA in wastewater using autosamplers or biosensors could be deployed efficiently. Fourteen criteria such as population density, patients with comorbidity, quarantine and hospital facilities, etc. are analysed using the data of 14 lac individuals infected by COVID-19 in the USA. The uniqueness of the proposed model is its ability to deal with the uncertainty associated with the data and decision maker's opinions using fuzzy logic, which is fused with Bayesian approach. The evidence-based virus detection in wastewater not only facilitates focused testing, but also provides potential communities for vaccine distribution. Consequently, governments can reduce lockdown periods, thereby relieving human stress and boosting economic growth. en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.subject Civil Engineering en_US
dc.subject Bayesian approach en_US
dc.subject Biosensors en_US
dc.subject Coronavirus en_US
dc.subject Fuzzy logic en_US
dc.subject Vaccine en_US
dc.subject Wastewater sampling en_US
dc.title Detecting SARS-CoV-2 RNA prone clusters in a municipal wastewater network using fuzzy-Bayesian optimization model to facilitate wastewater-based epidemiology en_US
dc.type Article en_US


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