Divalent ions are known to have a severe effect on the translocation of several antibiotic molecules into (pathogenic) bacteria. In the present study we have investigated the effect of divalent ions on the permeability of ...

The diffusion of pyrene, and thus other large planar aromatic molecules, is shown to take place in a shell close to the double-layer of cationic micelles. Perturbation of the pyrene π-electrons is demonstrated by vibronic ...

Solubility isotherms for MnBr2, CoBr2, NiBr2, CuBr2 and ZnBr2 in pyridine + chlorobenzene mixtures of varying composition have been determined at 20 and 30°C. Changes in the visible spectra of CoBr2, NiBr2 and CuBr2 with ...

The relationships developed for the variation of rate with dielectric constants have been extended to include effects derived from changes in solvent structure in order to interpret the linear plots for log (rate constant) ...

In the past two decades, molecular dynamics simulations have become the method of choice for elucidating the transport mechanisms of ions through various membrane channels. Often, these simulations heavily rely on classical ...

The permeation of (neutral) molecules through nanopores in the presence of external voltages depends on several factors including pore electrostatics, electrophoretic force, and electro-osmotic drag. In earlier single-channel ...

Despite tremendous successes in the field of antibiotic discovery seen in the previous century, infectious diseases have remained a leading cause of death. More specifically, pathogenic Gram-negative bacteria have become ...

Wir quantifizieren den Fluss von Protamin (Ptm) durch CymA, einen passivem Membrankanal zur Aufnahme von Cyclodextrin. Unter Verwendung eines Fluoreszenztests auf Reporterpaarbasis konnten wir den Eintritt von Ptm in ...

Channels in the outer membrane of Gram-negative bacteria provide essential pathways for the controlled and unidirectional transport of ions, nutrients and metabolites into the cell. At the same time, the outer membrane ...

Biological nanopores have been at the focus of numerous studies due to their role in many biological processes as well as their (prospective) technological applications. Among many other topics, recent studies on nanopores ...