Acute kidney injury (AKI) in diabetic conditions often advances to chronic kidney disease (CKD), exacerbated by ischemia–reperfusion injury (IRI) through pathomechanisms such as endoplasmic reticulum (ER) stress and ...

Acute kidney injury (AKI) is a significant clinical issue with potential long-term consequences, as even a single episode can progress to chronic kidney disease (CKD). The AKI-to-CKD transition involves complex pathophysiology, ...

A series of pyrazole-pyrazoline substituted with benzenesulfonamide were synthesized and evaluated for their antimalarial activity in vitro and in vivo. The compounds were active against both chloroquine (CQ) sensitive ...

Sodium trifluoromethanesulfonate, and glacial acetic acid selectively catalyzed the synthesis of dihydroquinoline via Friedländer annulation. The synthesized dihydroquinoline analogues coupled with different amines by the ...

The NorA efflux pump decreases the intracellular concentration of fluoroquinolones (ciprofloxacin, norfloxacin) by effluxing them from Staphylococcus aureus cells. The synthesis of novel acrylohydrazide derivatives was ...

Chemotherapy is one of the most common treatments for cancer that uses one or more anti-cancer drugs as a part of the standardized chemotherapy regimen. Cytotoxic chemicals delay and prevent cancer cells from multiplying, ...

Staphylococcus aureus (S. aureus) is responsible for several community and hospital-acquired infections with life-threatening complications such as bacteraemia, endocarditis, meningitis, liver abscess, and spinal cord ...

An algorithm is given to solve simultaneously two sets of equations, the first linear in the logarithm of the unknowns and the second linear in the unknowns. Newton's method coupled with an adapted relaxation technique is ...

Heats of adsorption, sticking probabilities and temperature programmed desorption spectra are reported for nitrogen on polycrystalline tungsten at 290 and 222 K. The initial heat of adsorption at 290 K was found to be 380 ...

Two methods of solution of the integral equation describing the physical adsorption of gases on polysorptic surfaces have recently been developed. The derived algorithms, HILDA and CAEDMON, are compared in detail by applying ...