Browsing by Author "Jha, Anil"
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Item Catalyst-Free One-Pot Tandem Reduction of Oxo and Ene/Yne Functionalities by Hydrazine: Synthesis of Substituted Oxindoles from Isatins(Wiley, 2014-04-15) Jha, AnilAn unprecedented hydrazine-mediated tandem reduction of oxo and N-ene/yne functionalities of substituted isatins is reported to access various oxindoles. The reaction is performed by treating N-(2-alkenyl)/propargylisatins with hydrazine hydrate under catalyst-free refluxing conditions. The reduction proceeds efficiently without the aid of any catalyst at ambient pressure.