Department of Pharmacy

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Author: search.filters.author.Gaikwad, Anil BhanudasSubject: search.filters.subject.Autophagy

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    ULK1 as a therapeutic target in kidney diseases: Current perspective
    (Taylor & Francis, 2024-11) Gaikwad, Anil Bhanudas
    Globally, ~850 million people are affected by different kidney diseases. The pathogenesis of kidney diseases is intricate, where autophagy is crucial for maintaining kidney homeostasis. Iteliminates damaged organelles, thus reducing renal lesions and allowing tissue regeneration. Therefore, targeting various autophagy proteins, e.g. Unc–51–like autophagy-activating kinase 1 (ULK1), is emerging as potential therapeutic strategy against kidney disease.
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    Management of inflammaging in kidney diseases: focusing on the current investigational drugs
    (Taylor & Francis, 2024-10) Gaikwad, Anil Bhanudas
    To improve kidney disease treatments, it is crucial to understand how inflammaging affects patients´ longevity. We could potentially slow down kidney disease progression and enhance longevity by targeting specific pathways involved in inflammaging with potential drugs.