BITS Faculty Publications
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Item Ultrasensitive surface plasmon resonance-based biosensor for efficient detection of SARS-CoV-2 Virus in the near-infrared region(2024) Grover, Nitika; Arora, PankajThis work offers an ultra-sensitive multilayered surface plasmon resonance (SPR)-based biosensor that uses angular interrogation in the near-infrared (NIR) region to detect the novel coronavirus (SARS-CoV-2). The multi-layered biosensor consists of the bimetallic layer (Aluminum (Al) & Gold(Au)), a dielectric layer (MgF2), and an optimized number of 2D nanomaterial (MoS2) layers. The proposed SPR sensor is engineered using the transfer matrix and finite element methods to achieve high sensitivity, the figure of merit (FOM), and detection accuracy. The selection of plasmonic metal and optimization for the different layers have been proved crucial to improving the performance parameter of the proposed sensor. The biosensor configuration (Glass prism/Al/Au/MgF2/MoS2/sensing sample) is observed to exhibit the highest sensitivity of 372°/RIU, FOM of 1690 RIU-1, and detection accuracy of 4.54 degree-1 using the strong binding efficiency of the MoS2 layer and the high dielectric constant of the MgF2 layer. According to the investigation's findings, the proposed SPR-based biosensor exhibits excellent performance in the NIR region, demonstrating accurate real-time detection capabilities that will facilitate its use in field or clinical point-of-care testing applications.Item TiO2-FG-based plasmonic sensor with enhanced figure of merit for sensing applications: A numerical approach(Elsevier, 2025-09) Grover, Nitika; Arora, PankajA refractive index-based surface plasmon resonance sensor using a multilayer heterostructure in the Kretschmann configuration is proposed for the near-infrared region. In the proposed configuration, aluminum is used as a plasmonic metal, titanium dioxide is used as a dielectric layer, and a fluorinated graphene (FG) layer is used as a 2D nanomaterial to enhance the performance parameters. A thorough comparative study is conducted between popularly used titanium compounds: Titanium dioxide (TiO2) and Titanium disilicide (TiSi2). For the proposed SPR sensor, each layer is engineered and optimized on the grounds of linewidth, detection accuracy (DA), and Figure of Merit (FOM), which are the critical performance parameters. To this end, the geometrical parameters are calculated using the transfer matrix method and analyzed meticulously to find the optimum trade-off points. The proposed sensor is numerically tested efficiently to sense different concentrations of hemoglobin in human blood. For the angle interrogation technique at the wavelength of 1550 nm, the sensor provides an enhanced FOM of 462.8 RIU−1 and a DA of 4 degrees−1. Thus, the proposed design opens a broader window for bio-sensing applications because of the advantages TiO2 and FG layers offer in enhancing the sensing parameters.Item Design and comparative analysis of aluminum-MoS2 based plasmonic devices with enhanced sensitivity and Figure of Merit for biosensing applications in the near-infrared region(Elsevier, 2021-02) Arora, PankajAluminum (Al)-Molybdenum Disulfide (MoS2) based plasmonic structures act as excellent biosensors when exploited in the near-infrared region. While Al is economical as well as compatible with the optoelectronic devices, MoS2 is an emerging 2D nanomaterial with the promise of initiating better plasmonic activity. Based on Kretschmann's arrangement, we have explored angular interrogation over four different combinations of heterostructures with Al as the plasmonic metal layer, at a wavelength of 1550 nm. After studying the effect of Al thickness on the conventional configuration, the intermediate layers between the metal layer and the analyte were optimized. Inclusion of graphene along with MoS2 results in better interaction with the sensing medium. The effect of including silicon is also studied for sensitivity enhancement. In addition, a comparative analysis of sensor performances of the proposed devices is presented taking into account the two important parameters i.e. sensitivity as well as the Figure of Merit (FOM). Among the optimized multi-layered MoS2 based configurations, a maximum sensitivity of about 141°/RIU is obtained along with FOM of about 335.13 RIU−1. Finally, the single-stranded DNA sensing on the proposed devices shows that the structures can be used as a highly sensitive refractive index biosensor for bio-medical applications.Item Graphene decorated aluminum-nanostructure based plasmonic device with enhanced sensitivity and figure of merit using both wavelength and angle interrogation(Elsevier, 2022-07) Arora, PankajIn this work, we have proposed graphene decorated Aluminum (Al) nanostructure-based plasmonic device for sensing in the near-infrared region where the same engineered plasmonic device can be used under both angle as well as wavelength interrogation with high sensitivity and Figure of Merit (FOM) simultaneously. A detailed analysis using rigorous coupled-wave analysis is carried out to prove the feasibility of the proposed plasmonic device with the same designed parameters to operate in two interrogation modes, which is impossible in conventional prism configuration. The performance parameters, sensitivity, and FOM are found to be 1000 nm/RIU and 333.33RIU−1 during wavelength interrogation and 119º/RIU and 318.91RIU−1 for the angle interrogation respectively. Finally, the biosensing application is carried out by demonstrating the glucose concentration detection in the urine samples. The proposed Al-based plasmonic device decorated with graphene layer has the advantages of being cost-effective and possessing real-time sensing capability, paving the way for biomedical applications in the near-infrared region.