BITS Faculty Publications

Permanent URI for this communityhttp://localhost:4000/handle/123456789/1867

Browse

Filters

2023 - 20244

Settings

Author: search.filters.author.Bhatt, GeetaSubject: search.filters.subject.Mechanical engineering

Search Results

Now showing 1 - 4 of 4
  • No Thumbnail Available
    Item
    Basic principles of impedance spectroscopy
    (CRC Press, 2023) Bhatt, Geeta
    Impedance spectroscopy of biomolecules is a growing domain that deals with the study and analysis of various analyte molecules to express high-utility applications. The analytes can be directly extracted from the environment or are derived from nature through some biological/biochemical processes. The common biological analytes are drugs, DNA/RNA, cells, pathogenic bacteria, enzymes, ions, and gases. Impedance analysis measures the impedance characteristics of an analyte over a long-range frequency sweep and interprets its behavior for various frequency domains. This detection method can be utilized for analysis in an independent or integrated format with various discrete analysis/supporting techniques. Along with extensive application in the biomedical field, this technique is also used in several other applications like the analysis of electroactive polymer thin films, colloids, lubricants, paints, and batteries/fuel cells. This chapter explains the utility of impedance analysis through a detailed explanation of fundamental principles, its several components, equivalent circuit diagrams, and their common applications.
  • No Thumbnail Available
    Item
    Impedance spectroscopy and its application in biological detection
    (CRC Press, 2023-12) Bhatt, Geeta
    This book includes basics of impedance spectroscopy technology, substrate compatibility issues, integration capabilities, and several applications in the detection of different analytes. It helps explore the importance of this technique in biological detection, related micro/nanofabricated platforms and respective integration, biological synthesis schemes to carry out the detection, associated challenges, and related future directions. The various qualitative/quantitative findings of several modules are summarized in the form of the detailed descriptions, schematics, and tables. Features: Serves as a single source for exploring underlying fundamental principles and the various biological applications through impedance spectroscopy Includes chapters based on nonbiological applications of impedance spectroscopy and IoT-enabled impedance spectroscopy-based methods for detection Discusses derivations, substrates, applications, and several integrations Describes micro/nanofabrication of impedance-based biological sensors Reviews updated integrations like digital manufacturing and IoT
  • No Thumbnail Available
    Item
    A historical perspective on impedance spectroscopy and its application in biological detection
    (CRC Press, 2023) Bhatt, Geeta
    Electrical/electrochemical impedance spectroscopy (EIS) is a generalized term for the technique in which the impedance response of a system/analyte is generally measured over a particular range of frequencies to analyze its behavior. Sometimes, the measurement can also be taken over the time domain, and then Fourier-transformed to the frequency domain. The impedance measurements recorded in a particular medium interpret the behavior of the analyte, which is further adapted as per the user’s needs. The EIS measurements can be utilized for any kind of analyte, viz. biological/nonbiological and solid/liquid/gas, provided they show a noticeable impedance change. Hence, EIS has a large domain of applicability and with a view to enhance its capability, extensive research in this field is being done with various analytes. To offer the knowledge of this field’s most recent literature to researchers and experimentalists, this book primarily compiles the various studies available in the impedance spectroscopy domain. The chapters of this book have been organized to initially detail the fundamentals of the EIS process, its device fabrication aspects, various substrate/material requirements, the utility of microfluidic integration, its applications (mostly biological), various technological integrations, and, finally, the challenges in EIS implementation.
  • No Thumbnail Available
    Item
    Evolution of 3d printing technology in fabrication of microfluidic devices and biological applications: a comprehensive review
    (Sage, 2024-04) Bhatt, Geeta
    Lab-on-a-chip or LOC is a term that is used to describe microfluidic devices that integrate multiple analyte detection, which are normally carried out in a laboratory, into one micro-chip unit and may have applications in diverse fields such as electronics, medicine and biomedical domains. Even though microfluidics has advanced greatly during the past decade due to increased needs for portability, reduced sample requirement and multiple analyte detection capabilities biological research has not adopted the technology at the required pace. This may be owing to the time-consuming and expensive process involved in the microfabrication of biochips, the requirement of specialised setup facilities and the extremely high cost associated with microfluidics as compared to conventional technologies. In recent years, three-dimensional (3D) printing has piqued curiosity in the scientific community. It has the potential to create complex, high-resolution structures and that too in a short timeframe depending upon device complexity. This could inspire progressive research in microfluidics, particularly finding applications in biomedical engineering and point-of-care diagnostics. This article gives an overview of how 3D printing aids in the manufacture of microfluidic devices for biological applications, as well as the existing 3D printing methods which are utilised for fabrication and the future perspective in the development of microfluidic devices.