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Author: search.filters.author.Sah, Ajay KumarSubject: search.filters.subject.Analgesic

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    The synthesis of amino acid derived glycoconjugates and the investigation of their anti-inflammatory and analgesic properties
    (2014) Sah, Ajay Kumar
    A series of 4,6-O-ethylidene-β-D-glucopyranosylamine derived glycoconjugates containing amino- and aromatic acids have been synthesized. All these molecules have been tested for their anti-inflammatory and analgesic activity on Wistar rat and Swiss Albino mice respectively. The anti-inflammatory studies were explored using a carrageenan induced paw oedema model while an acetic acid induced writhing model was adapted for the analgesic studies. All of the compounds exhibited anti-inflammatory and analgesic activity in the range of 63–84% and 86–94% respectively.