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Author: search.filters.author.Sharma, Bhupendra KumarSubject: search.filters.subject.Nanoparticles

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    Entropy generation optimization for the electroosmotic MHD fluid flow over the curved stenosis artery in the presence of thrombosis
    (Springer Nature, 2023-09) Sharma, Bhupendra Kumar
    The present study deals with the entropy generation analysis on the flow of an electrically conductive fluid (Blood) with -suspended nanoparticles through the irregular stenosed artery with thrombosis on the catheter. The fluid flow can be actuated by the interactions of different physical phenomena like electroosmosis, radiation, Joule heating and a uniform radial magnetic field. The analysis of different shapes and sizes of the nanoparticle is considered by taking the Crocine model. The velocity, temperature, and concentration distributions are computed using the Crank–Nicholson method within the framework of the Debye–Huckel linearization approximation. In order to see how blood flow changes in response to different parameters, the velocity contour is calculated. The aluminium oxide nanoparticles employed in this research have several potential uses in biomedicine and biosensing. The surface’s stability, biocompatibility, and reactivity may be enhanced by surface engineering, making the material effective for deoxyribonucleic acid sensing. It may be deduced that the velocity profile reduces as the nanoparticle’s size grows while depicts the reverse trend for the shape size. In a region close to the walls, the entropy profile decreases, while in the region in the middle, it rises as the magnetic field parameter rises. The present endeavour can be beneficial in biomedical sciences in designing better biomedical devices and gaining insight into the hemodynamic flow for treatment modalities.
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    Electromagnetohydrodynamics Casson pulsatile nanofluid flow through a bifurcated stenosed artery: Magnetically targeted drug delivery
    (AIP, 2023-11) Sharma, Bhupendra Kumar
    The current study is centered on the application of magnetically targeted drug delivery in a constricted vertical bifurcated artery utilizing Fe O nanoparticles. The arterial stenosis is characterized by a bell-shaped narrowing in the parent artery and overlapping narrowing in the daughter artery. The blood is regarded as exhibiting the rheological behavior of a Casson fluid. The temperature-dependent nature of blood viscosity is postulated, and Reynold’s viscosity model describes it. This study examines the impact of electromagnetohydrodynamics (EMHD), body acceleration, Joule heating, and viscous dissipation. The assumption of a no-slip velocity condition is made at the walls of the artery. The governing equations are subjected to a process of non-dimensionalization and simplification, employing the mild-stenosis approximation. The resulting equations are subsequently solved in MATLAB by employing the finite-difference Crank–Nicolson technique. Entropy plays a significant role during any treatment or surgery; therefore, the present problem addresses entropy generation minimization. The results for velocity, temperature, wall shear stress, flow rate, impedance, heat transfer rate, entropy generation number, and Bejan number are represented graphically. The velocity contours illustrate that the flow velocity enhances with the Casson fluid and particle mass parameters. Furthermore, the number of trapped bolus also increases in the daughter artery. The nanofluid velocity and particle velocity decrease with an increase in the particle concentration parameter in the parent artery and the daughter artery. Entropy declines with the temperature difference parameter increment, whereas the Bejan number enhances. Magnetite (Fe O ⁠) nanoparticles have various applications owing to their biocompatibility, elevated magnetic susceptibility, chemical stability, non-toxic nature, and cost-effectiveness.
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    Computer simulation of two phase power-law nanofluid of blood flow through a curved overlapping stenosed artery with induced magnetic field: entropy generation optimization
    (Emerald, 2024-02) Sharma, Bhupendra Kumar
    The purpose of this study is to determine the impact of two-phase power law nanofluid on a curved arterial blood flow under the presence of ovelapped stenosis. Over the past couple of decades, the percentage of deaths associated with blood vessel diseases has risen sharply to nearly one third of all fatalities. For vascular disease to be stopped in its tracks, it is essential to understand the vascular geometry and blood flow within the artery. In recent scenarios, because of higher thermal properties and the ability to move across stenosis and tumor cells, nanoparticles are becoming a more common and effective approach in treating cardiovascular diseases and cancer cells.
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    The significant role of Darcy–Forchhiemer with integrated hybrid nanoparticles (Graphene and TiO2) on dusty nanofluid flow subjected to heat conduction
    (Taylor & Francis, 2024-04) Sharma, Bhupendra Kumar
    The thermal analysis of two-phase models that deal with the fluid and dusty phases has been considered. This study instigates the flow of a non-miscible, dusty hybrid nanofluid over a stretching cylinder with Darcy–Forchheimer permeability in the presence of thermal radiation. The mathematical model is based on the single-phase nanofluid model, which features modified thermophysical characteristics. This innovative flow model explores how important it is to enhance the concentration of dust particles in fluid dynamics. Hybrid nanoparticles are substituted for nanoparticles in a conventional case to accelerate the heat transfer rate of the fluid. Therefore, in this study, the magnetohydrodynamic flow of hybrid nanofluids and heat transfer of non-Newtonian dusty fluids with suspensions of hybrid nanoparticles have been examined. The appropriate dimensionless variables are used to convert the governing periodic model into a non-dimensional form. The finite-difference-based bvp5c algorithm is used through Matlab for numerical analysis of the set of obtained ordinary differential equations. The graphs explored the influences of relatable factors over the profiles of mass, heat, and velocity transfers. It is observed that with intensifying values of Eckert number (Ec) and Biot number (Bi), the temperature of both phases increased at a significant level, and the velocity decreased with increasing intensity of the magnetic field. The computational results of velocity, core temperature, and intensity dispersion are significant for both aspects. Furthermore, it is observed that both the fluid and dust phases exhibit declining behavior as a result of the impact of porosity, mass concentration, and magnetism on the flow stream. Moreover, it is noticed that both the dust phase temperature 𝜃𝑝⁡(𝜂) and fluid phase temperature 𝜃⁡(𝜂) intensified with the high intensity of magnetic field and thermal radiation. The missile nozzles, nuclear power plants for aerospace and gaseous-core nuclear rocket systems, and the radiation are considered for evaluating heating significance.
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    Electroosmotic microchannel flow of blood conveying copper and cupric nanoparticles: Ciliary motion experiencing entropy generation using backpropagated networks
    (Wiley, 2024-03) Sharma, Bhupendra Kumar
    A novel mathematical model for a hybrid (Cu–CuO/blood) Jeffrey nanofluid passing a vertical symmetric microchannel along with an electroosmosis pump is presented. The focuses on the advancement of mathematical modeling techniques, its comprehensive analysis of microfluidic system dynamics, and its potential to inform the optimal design of devices using nanofluids with broad applications in various fields. Arrhenius's law is used to analyze endothermic–exothermic reactions and activation energy. The governing partial differential equations of the fixed frame are transformed into ordinary differential equations of the wave frame using self-similarity transformations. Low Reynolds number and long-wavelength approximations helped to find solutions of the equations by applying a suitable BVP solver in MATLAB. The fluid's velocity, temperature, concentration, and electroosmosis properties are studied graphically. Two-dimensional contour plots of fluid velocity and three-dimensional surface plots of fluid properties are discussed. Physically significant quantities of mass transfer rate, skin friction coefficient, entropy generation, and heat transfer rate are studied using contour plots. Artificial neural network simulation using Bayesian regularization backpropagation algorithms is analyzed for training state, error histogram, fit, performance, and regression plots. Conclusively, the comprehensive analysis of the fluid dynamics, entropy generation, mass and heat transfer, and in the microchannel, coupled with the successful implementation of artificial neural network simulation, contributes to an improved understanding of the system's behavior. Entropy generation was raised for enhanced Brownian motion number and reduced values of thermophoresis, activation energy, and endothermic–exothermic reaction parameters. This study's results can be used to improve the efficiency and effectiveness of microfluidic devices used in fields as diverse as electrical cooling and medicine delivery.
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    Radiation effect on MHD copper suspended nanofluid flow through a stenosed artery with temperature-dependent viscosity
    (IJNAA, 2022-08) Sharma, Bhupendra Kumar
    In the present paper, the effects of radiation, variable viscosity, and the inclination of the artery on copper nanofluid through composite stenosis with chemical reaction are discussed. The viscosity of blood is varied with temperature as represented in the Reynolds viscosity model. The coupled nonlinear equations of the nanofluid model are simplified by considering the mild stenosis case. The governing equations are solved numerically by applying the Finite Difference Method. The effects of the physical parameters on the velocity, temperature, and concentration along the radial axis have been studied and are physically interpreted for medical applications. The effect of shear stress along the increasing height of stenosis has been explained with the help of graphs. The proposed work will be beneficial to clinicians, hematologists, and biomedical engineers because they serve as useful approximations, which are capable of throwing some light toward the understanding of the genesis of pathological states, like arteriosclerosis as well as the mechanism of gaseous exchanges that take place within arteries and capillaries.
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    Computer Simulations of EMHD Casson Nanofluid Flow of Blood through an Irregular Stenotic Permeable Artery: Application of Koo-Kleinstreuer-Li Correlations
    (MDPI, 2023-02) Sharma, Bhupendra Kumar
    A novel analysis of the electromagnetohydrodynamic (EMHD) non-Newtonian nanofluid blood flow incorporating CuO and Al2O3 nanoparticles through a permeable walled diseased artery having irregular stenosis and an aneurysm is analyzed in this paper. The non-Newtonian behavior of blood flow is addressed by the Casson fluid model. The effective viscosity and thermal conductivity of nanofluids are calculated using the Koo-Kleinstreuer-Li model, which takes into account the Brownian motion of nanoparticles. The mild stenosis approximation is employed to reduce the bi-directional flow of blood to uni-directional. The blood flow is influenced by an electric field along with a magnetic field perpendicular to the blood flow. The governing mathematical equations are solved using Crank-Nicolson finite difference approach. The model has been developed and validated by comparing the current results to previously published benchmarks that are peculiar to this study. The results are utilized to investigate the impact of physical factors on momentum diffusion and heat transfer. The Nusselt number escalates with increasing CuO nanoparticle diameter and diminishing the diameter of Al2O3 nanoparticles. The relative % variation in Nusselt number enhances with Magnetic number, whereas a declining trend is obtained for the electric field parameter. The present study’s findings may be helpful in the diagnosis of hemodynamic abnormalities and the fields of nano-hemodynamics, nano-pharmacology, drug delivery, tissue regeneration, wound healing, and blood purification systems.