Design, Synthesis and In Vitro Evaluation of 4-Oxo-6-Substituted Phenyl- 2-Thioxo1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile Derivatives as HIV Integrase Strand Transfer Inhibitors
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Date
2021-11
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Publisher
Bentham Science
Abstract
To design, synthesis and in vitro evaluation of 4-oxo-6-substituted phenyl-2- thioxo1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives as HIV integrase strand transfer inhibitors
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Keywords
Pharmacy, HIV-1 integrase, Anti-HIV, Docking studies, Strand transfer inhibitors, Tetrahydropyrimidine-5-carbonitriles