Design, Synthesis and In Vitro Evaluation of Piperazine Incorporated Novel Anticancer Agents
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Date
2018
Authors
Journal Title
Journal ISSN
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Publisher
Bentham Science
Abstract
Novel 4-(3-(4-ethylpiperazin-1-yl)propoxy)-N-phenylbenzamide derivatives (C-1 to C-10) and (4-(3-(4-ethylpiperazin-1-yl)propoxy)phenyl)(4-(2-methoxyphenyl)piperazin-1- yl)ethanone derivatives (C-11 to C-16) were designed and synthesized by pharmacophore approach.
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Keywords
Pharmacy, Carcinoma, Cytotoxocity, Epidermal growth factor receptor inhibitors, Ethyl piperazine, Cancer line