Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy

dc.contributor.author	Gaikwad, Anil Bhanudas
dc.date.accessioned	2023-12-18T11:59:10Z
dc.date.available	2023-12-18T11:59:10Z
dc.date.issued	2009-01
dc.description.abstract	Curcumin has been used to treat cancer, diabetes and other pathologies. However, little is known regarding its role in altering post-translational modifications of histone H3. A recent report suggests that acute hyperglycaemia induces a global down-regulation of gene expression in human tissues and epigenetic regulation of gene expression could be a novel mechanism underlying the pathological processes of hyperglycaemia. The present study was undertaken to examine changes in histone modification by curcumin treatment which prevents development of type I diabetic nephropathy.	en_US
dc.identifier.uri	https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1038/sj.bjp.0707666
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13439
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Pharmacy	en_US
dc.subject	Diabetic nephropathy	en_US
dc.subject	Streptozotocin	en_US
dc.subject	Cancer	en_US
dc.title	Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy	en_US
dc.type	Article	en_US

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