Asymmetric synthesis of a 3,4-substituted pyrrolidine by l-proline catalyzed direct enolexo aldolization

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Date

2007-06-11

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Elsiever

Abstract

The asymmetric synthesis of a 3,4-substituted N-tosyl pyrrolidine has been achieved by using l-proline catalyzed 5-enolexo aldolization with high enantio and diastereoselectivity.

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Keywords

Chemistry, Asymmetric synthesis, Pyrrolidines, l-proline

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