Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy
| dc.contributor.author | Mahesh, R. | |
| dc.date.accessioned | 2023-11-20T04:03:44Z | |
| dc.date.available | 2023-11-20T04:03:44Z | |
| dc.date.issued | 2014-08 | |
| dc.description.abstract | Olfactory bulbectomy (OBX) is a widely used model for antidepressant screening and known to induce neurodegeneration in several brain areas. Our earlier studies demonstrated that etazolate produced antidepressant-like effects in behavioral despair models of depression; however, the potential role of etazolate on behavior and morphological changes in the hippocampus region along with its underlying mechanism(s) following OBX has not been adequately addressed. | en_US |
| dc.identifier.uri | https://link.springer.com/article/10.1007/s00213-014-3705-0 | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13168 | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer | en_US |
| dc.subject | Olfactory bulbectomy (OBX) | en_US |
| dc.subject | Phosphodiesterase-4 | en_US |
| dc.subject | Etazolate | en_US |
| dc.title | Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy | en_US |
| dc.type | Article | en_US |
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