Camel Milk α-lactalbumin As A Potential Anticancer Molecule: A Bioinformatics Analysis

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Date

2020

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Research Journal of Pharmaceutical, Biological and Chemical Sciences

Abstract

α-lactalbumin-Oleic acid complex derived from milk is well known to have anti-cancer properties in many diverse mammalian species including humans, goats and cows. The objective of the current study is to see if α-lactalbumin present in camel’s milk too can serve as a potential anti-cancer molecule in its complex form. A comparative evaluation of α-lactalbumin structure among four mammalian species, viz, Camelusferus, Bostaurus, Homo sapiens, and Capra hircus has been made between the nucleotide sequences and structures of protein. Furthermore, the physico-chemical properties, amino acid composition, position of disulfide bridge formation in these species has been compared. The outcome of the present study suggests the presence of an anti-cancer property in the α-lactalbumin of camel, as has been experimentally observed in the other three species.

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Keywords

Biology, Camel milk, Anti-cancer, HAMLET, Computational analysis, DNA, Physicochemical properties, Amini acid

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