Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors

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dc.contributor.authorPaul, Atish Tulshiram
dc.date.accessioned2024-01-02T04:51:34Z
dc.date.available2024-01-02T04:51:34Z
dc.date.issued2022-11
dc.description.abstractObesity is a multifactorial metabolic disease characterised by excessive accumulation of triglycerides. The prevalence and morbidity rates associated with obesity are increasing tremendously, posing a significant risk to society. Pancreatic lipase (PL) is a key enzyme responsible for the digestion of dietary triglycerides; hence its inhibition is considered an attractive target in obesity.en_US
dc.identifier.urihttps://www.ingentaconnect.com/content/ben/lddd/2022/00000019/00000011/art00003
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13590
dc.language.isoenen_US
dc.publisherBentham Scienceen_US
dc.subjectPharmacyen_US
dc.subjectObesityen_US
dc.subjectEnzyme inhibitionen_US
dc.subjectFluorescence spectroscopyen_US
dc.subjectMolecular dockingen_US
dc.subjectPancreatic lipaseen_US
dc.subjectThiazolidinediones (TZDs)en_US
dc.titleDesign and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitorsen_US
dc.typeArticleen_US

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