P0527 Hyperglycemia-associated Acute Kidney Injury Increases the Susceptibility Towards Neurological Dysfunction: Role of Angiotensin Ii Type 2 Receptor and Angiotensin-converting Enzyme 2

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dc.contributor.authorGaikwad, Anil Bhanudas
dc.date.accessioned2023-12-27T07:14:49Z
dc.date.available2023-12-27T07:14:49Z
dc.date.issued2020-06
dc.description.abstractIn clinical settings, diabetics remain on higher risk of ischemic renal injury (IRI) than nondiabetic patients. In addition, IRI predisposes distant organs to dysfunction such as neurological impairments via activation of the pressor arm of renin-angiotensin system (RAS). In contrast, the role of depressor arm of RAS on IRI-associated neurological sequalae remains elusive. Hence, this study explored the role of angiotensin II type 2 receptor (AT2R) and angiotensin-converting enzyme 2 (ACE2) in IRI-associated neurological dysfunctions under nondiabetic (ND) and diabetes mellitus (DM) condition.en_US
dc.identifier.urihttps://academic.oup.com/ndt/article/35/Supplement_3/gfaa142.P0527/5852684
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13532
dc.language.isoenen_US
dc.publisherOUPen_US
dc.subjectPharmacyen_US
dc.subjectCytokine stormen_US
dc.subjectIschemic renal injury (IRI)en_US
dc.subjectEnzyme inhibitionen_US
dc.titleP0527 Hyperglycemia-associated Acute Kidney Injury Increases the Susceptibility Towards Neurological Dysfunction: Role of Angiotensin Ii Type 2 Receptor and Angiotensin-converting Enzyme 2en_US
dc.typeArticleen_US

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