DRP1-mediated mitochondrial dynamics orchestrate EMT in glioblastoma cells
| dc.contributor.author | Chowdhury, Shibasish | |
| dc.contributor.author | Chowdhury, Rajdeep | |
| dc.contributor.author | Mukherjee, Sudeshna | |
| dc.date.accessioned | 2026-01-08T11:23:31Z | |
| dc.date.available | 2026-01-08T11:23:31Z | |
| dc.date.issued | 2025-12 | |
| dc.description.abstract | Epithelial to mesenchymal transition (EMT), a differentiation process, frequently imparts invasive properties in Glioblastoma Multiforme (GBM), which leads to a poor prognosis. Cells lose apical-basal polarity, cell-cell connections, and/or chemo-resistance during EMT, which can result in the spread of cancer and the acquisition of additional stem cell-like traits. It is unclear how organelle dynamics influence EMT in this respect. The interaction between cytoskeletal and mitochondrial regulators governing GBM cell EMT is explored in this article. | en_US |
| dc.identifier.uri | https://www.biorxiv.org/content/10.64898/2025.12.12.694080v1.abstract | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/20506 | |
| dc.language.iso | en | en_US |
| dc.subject | Biology | en_US |
| dc.subject | Epithelial–mesenchymal transition (EMT) | en_US |
| dc.subject | Glioblastoma multiforme (GBM) | en_US |
| dc.subject | Mitochondrial dynamics | en_US |
| dc.subject | Cytoskeletal regulation | en_US |
| dc.title | DRP1-mediated mitochondrial dynamics orchestrate EMT in glioblastoma cells | en_US |
| dc.type | Article | en_US |
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