Biomimetic Reduction of Nimesulide with NaBH4 Catalyzed by Metalloporphyrins

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Date

2002

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Volume Title

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J-Stage

Abstract

The biomimetic reduction of anti-inflammatory drug, nimesulide (1) with sodium borohydride catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides [TAPFe(III)Cl] has been studied in organic solvents under anaerobic and aerobic conditions.

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Keywords

Chemistry, Biomimetic reduction, Nimesulide, Metalloporhyrin

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