Dynamics of tuberculosis transmission with exogenous reinfections and endogenous reactivation

Abstract

We propose and analyze a mathematical model for tuberculosis (TB) transmission to study the role of exogenous reinfection and endogenous reactivation. The model exhibits two equilibria: a disease free and an endemic equilibria. We observe that the TB model exhibits transcritical bifurcation when basic reproduction number . Our results demonstrate that the disease transmission rate and exogenous reinfection rate plays an important role to change the qualitative dynamics of TB. The disease transmission rate give rises to the possibility of backward bifurcation for , and hence the existence of multiple endemic equilibria one of which is stable and another one is unstable. Our analysis suggests that may not be sufficient to completely eliminate the disease. We also investigate that our TB transmission model undergoes Hopf-bifurcation with respect to the contact rate and the exogenous reinfection rate . We conducted some numerical simulations to support our analytical findings.