Copper-Catalyzed Tandem Imine Formation, Sonogashira Coupling and Intramolecular Hydroamination: A Facile Synthesis of 3-Aryl-γ−carbolines

dc.contributor.author	Kumar, Anil
dc.contributor.author	Kumar, Dalip
dc.date.accessioned	2021-10-14T13:11:33Z
dc.date.available	2021-10-14T13:11:33Z
dc.date.issued	2021-11-25
dc.description.abstract	A one-pot, atom-economical multicomponent reaction of 2-bromoindole-3-carbaldehydes, alkynes and ammonia was developed in the presence of copper catalyst for the synthesis of a series of 3-aryl-γ−carboline derivatives in good to high yields. The developed reaction involved formation of imine followed by copper-catalyzed directed Sonogashira coupling and intramolecular hydroamination sequence of reactions. This multicomponent approach features mild reaction conditions and good functional group tolerance to access variety of 3-aryl γ-carbolines.	en_US
dc.identifier.uri	https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/slct.201702025
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2831
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Chemistry	en_US
dc.subject	Copper-Catalyzed	en_US
dc.subject	Sonogashira Coupling	en_US
dc.subject	Intramolecular Hydroamination	en_US
dc.title	Copper-Catalyzed Tandem Imine Formation, Sonogashira Coupling and Intramolecular Hydroamination: A Facile Synthesis of 3-Aryl-γ−carbolines	en_US
dc.type	Article	en_US

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