G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation

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dc.contributor.authorMajumder, Syamantak
dc.date.accessioned2021-10-02T17:48:07Z
dc.date.available2021-10-02T17:48:07Z
dc.date.issued2014
dc.description.abstractRecent evidence suggests G-protein–coupled receptor-2–interacting protein-1 (GIT1) overexpression in several human metastatic tumors, including breast, lung, and prostate. Tumor metastasis is associated with an increase in angiogenesis. We have showed previously that GIT1 is required for postnatal angiogenesis during lung development. However, the functional role of GIT1 in pathological angiogenesis during tumor growth is unknown.en_US
dc.identifier.urihttps://www.ahajournals.org/doi/10.1161/ATVBAHA.113.302689
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2422
dc.language.isoenen_US
dc.publisherPMCen_US
dc.subjectBiologyen_US
dc.subjectG-protein–coupled receptor kinaseen_US
dc.subjectCortactin; endothelial cellsen_US
dc.subjectinteracting protein-1en_US
dc.titleG-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formationen_US
dc.typeArticleen_US

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