Direct catalytic synthesis of densely substituted 3-formylpyrroles from imines and 1,4-ketoaldehydes
| dc.contributor.author | Kumar, Indresh | |
| dc.date.accessioned | 2021-10-27T04:27:54Z | |
| dc.date.available | 2021-10-27T04:27:54Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | A sustainable method for the direct access to highly substituted 3-formylpyrroles from 1,4-ketoaldehydes and imine via formal [3 + 2] cycloaddition is reported. This reaction involves a one-pot amine catalyzed chemoselective Mannich-cyclization-aerobic oxidation sequence with good to high yields. Further application of the gram scale reaction as well as synthesis of fully substituted 3-formylpyrrole is also shown. | en_US |
| dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra06581f | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3173 | |
| dc.language.iso | en | en_US |
| dc.publisher | RSC | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Synthesis | en_US |
| dc.subject | 3-formylpyrroles | en_US |
| dc.subject | Ketoaldehydes | en_US |
| dc.title | Direct catalytic synthesis of densely substituted 3-formylpyrroles from imines and 1,4-ketoaldehydes | en_US |
| dc.type | Article | en_US |
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