A facile synthesis of naturally occurring 5-(3-indolyl)oxazoles
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Date
2008-01-28
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Elsiever
Abstract
A simple and efficient synthesis of naturally occurring 5-(3-indolyl)oxazoles is described. The key steps of this convergent approach are the formation of a 3-tosyloxyacetyl-1-benzenesulfonylindole, a 3-amino-acetyl-1-benzenesulfonylindole hydrochloride and cyclodehydration of an α-acylaminoketone.
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Keywords
Chemistry, 5-(3-Indolyl)oxazoles, Hydroxy(tosyloxy)-iodobenzene, α-Acylaminoketones