AzaGly-Appended Peptidomimetics Structurally Related to PTR6154 as Potential PKB/Akt Inhibitors

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dc.contributor.authorShrivastava, Richa
dc.date.accessioned2024-01-19T10:22:18Z
dc.date.available2024-01-19T10:22:18Z
dc.date.issued2017-04
dc.description.abstractSynthesis of AzaGly-appended peptidomimetics with improved biological and biochemical properties. Robust synthesis of azapeptide on solid support is demonstrated without noticeable hydantoin formation. The azapeptide derived from the GSK-3β substrate exhibited improved properties in terms of Akt kinase inhibitory activity and basal degradation, proteolytic degradation, conformation and binding affinities.en_US
dc.identifier.urihttps://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201700031
dc.identifier.urihttps://dspace.bits-pilani.ac.in/xmlui/handle/123456789/13891
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectPharmacyen_US
dc.subjectPeptidomimeticsen_US
dc.subjectPKB/Akt Inhibitorsen_US
dc.titleAzaGly-Appended Peptidomimetics Structurally Related to PTR6154 as Potential PKB/Akt Inhibitorsen_US
dc.typeArticleen_US

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