Synthesis and Evaluation of 3-(1,3-dioxoisoindolin-2-yl)-N-substituted Phenyl Benzamide Analogues as HIV Integrase Strand Transfer Inhibitors
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Date
2019
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Publisher
Bentham Science
Abstract
A series of novel 3-(1,3-dioxoisoindolin-2-yl)-N-substituted phenyl benzamide derivatives was synthesized and tested in vitro against human immunodeficiency virus type-1 Integrase (HIV-1 IN).
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Keywords
Pharmacy, AIDS, HIV-1 integrase, IN inhibitors, N-substituted phenyl benzamide, Docking studies, Strand transfer inhibitors