Histone deacetylase inhibitor, Valproic acid, ameliorates insulin resistance induced cognitive deficit in mice

dc.contributor.authorTaliyan, Rajeev
dc.date.accessioned2023-12-14T06:47:06Z
dc.date.available2023-12-14T06:47:06Z
dc.date.issued2017-10
dc.description.abstractInsulin resistance has been reported as a strong risk factor for Alzheimer’s disease (AD). However the molecular mechanisms of association between these still remain elusive. Recently, elevated level of histone deacetylases (HDACs) and reduced histone acetylation has been reported in AD patients.Thus, targeting HDACs could provide a novel therapeutic strategy for treating these co-morbid condition.en_US
dc.identifier.urihttps://linkinghub.elsevier.com/retrieve/pii/S0022510X17326953
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13420
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectPharmacyen_US
dc.subjectInsulinen_US
dc.subjectHistone deacetylases (HDACs)en_US
dc.titleHistone deacetylase inhibitor, Valproic acid, ameliorates insulin resistance induced cognitive deficit in miceen_US
dc.typeArticleen_US

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