Differential stability of DNA based on salt concentration
| dc.contributor.author | Singh, Navin | |
| dc.date.accessioned | 2024-02-20T04:18:06Z | |
| dc.date.available | 2024-02-20T04:18:06Z | |
| dc.date.issued | 2016-05 | |
| dc.description.abstract | Intracellular positive ions neutralize negative charges on the phosphates of a DNA strand, conferring greater strength on the hydrogen bonds that connect complementary strands into a double helix and so confer enhanced stability. Beyond a certain value of salt concentration, the DNA molecule displays an unstable nature in vivo as well as in vitro. We consider a wide range of salt concentrations and study the stability of the DNA double helix using a statistical model. Through numerical calculations, we attempt to explain the different behavior exhibited by DNA molecules in this range. We compare our results with experimental data and find a close agreement. | en_US |
| dc.identifier.uri | https://link.springer.com/article/10.1007/s00249-016-1132-3 | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/14351 | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer | en_US |
| dc.subject | Physics | en_US |
| dc.subject | DNA strand | en_US |
| dc.subject | DNA molecules | en_US |
| dc.title | Differential stability of DNA based on salt concentration | en_US |
| dc.type | Article | en_US |
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