Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones
| dc.contributor.author | Kumar, Anil | |
| dc.date.accessioned | 2021-10-14T13:10:55Z | |
| dc.date.available | 2021-10-14T13:10:55Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(II)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand-free Heck reaction. Good to excellent yields (41–94%) were observed with excellent substrate scope and functional group tolerance. The developed method represents a practical strategy for the construction of bioactive isoindolo[2,1-b]isoquinolin-7(5H)-ones. | en_US |
| dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2019/ob/c9ob00440h | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2821 | |
| dc.language.iso | en | en_US |
| dc.publisher | RSC | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Copper | en_US |
| dc.subject | Palladium-catalyzed | en_US |
| dc.subject | Isoindolo | en_US |
| dc.title | Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones | en_US |
| dc.type | Article | en_US |
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