Ru(II)-catalyzed oxidative (4+3) C–H/C–H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol
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Date
2025-03
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RSC
Abstract
A ruthenium(II)-catalyzed direct oxidative (4+3) C–H/C–H annulation of 2-aryl-4H-pyrido[1,2-a]pyrimidin-4-ones with allyl alcohol has been described. The developed method yielded the corresponding annulated products in moderate to good yields. In addition, based on the control experimental results, a possible reaction mechanism has been proposed for the (4+3) C–H/C–H annulation reaction.
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Keywords
Chemistry, Ruthenium(II) catalysis, C–H/C–H activation, Allyl alcohols