ChemInform Abstract: Exploration of the CuAAC Reaction for the Synthesis of Novel 3-(Triazol-1-yl)methyl-imidazo[1,2-a]pyridines

Abstract

The archetypical CuAAC click chemistry is explored to assemble diverse 3-(triazol-1-yl)methyl-imidazo[1,2-a]pyridines. The approach is simple, general, and environmentally benign to generate a library of novel triazolo-imidazo[1,2-a]pyridine derivatives in good yield (30–90%).