Recent Progress in Hot Melt Extrusion Technology in Pharmaceutical Dosage Form Design
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Date
2022-09
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Publisher
Bentham Science
Abstract
The Hot Melt Extrusion (HME) technique has shown tremendous potential in transforming highly hydrophobic crystalline drug substances into amorphous solids without using solvents. This review explores in detail the general considerations involved in the process of HME, its applications and advances.
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Keywords
Pharmacy, Hot melt extrusion, Solvent-free processing, Sustained release, Nanotechnology, PAT technology