Therapeutic Advances in the Treatment of Alzheimer's Disease: Present and Future

Simple item page
dc.contributor.authorJadhav, Hemant R.
dc.date.accessioned2023-11-30T10:25:04Z
dc.date.available2023-11-30T10:25:04Z
dc.date.issued2011-11
dc.description.abstractThe underlying pathogenesis of Alzheimer's disease (AD) is complex and is still under exploration. This has hampered the attempts to design highly selective and potent agents to treat AD. This review summarizes the present status of AD, present strategies and hypotheses (with underlying upstream and downstream events) for designing new drugs for AD. It also appraises the drugs based on present strategies that are in various stages of clinical trials, failures and the reasons for their failure. Further, it describes the future strategies being adopted for the anti-alzheimer's drug design. The recent approaches like immunotherapy, multi-targeted drug ligand design, usage of electromagnetic radiation and nanoparticle-mediated drug delivery are upcoming tools to overcome the impediment and have been discussed in this review.en_US
dc.identifier.urihttps://www.ingentaconnect.com/content/ben/cdth/2011/00000006/00000003/art00002
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13287
dc.language.isoenen_US
dc.publisherBentham Scienceen_US
dc.subjectPharmacyen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectAmyloid cascade hypothesisen_US
dc.subjectCholinestrase inhibitorsen_US
dc.subjectSecretase inhibitorsen_US
dc.subjectSecretase inhibitorsen_US
dc.subjectMulti-targeted drug ligand designen_US
dc.titleTherapeutic Advances in the Treatment of Alzheimer's Disease: Present and Futureen_US
dc.typeArticleen_US

Files

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Department of Pharmacy