Histamine H3 Receptor Function and Ligands: Recent Developments
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Date
2013
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Publisher
Bentham Science
Abstract
Histamine H3 receptors are found mostly in central nervous system involved in the regulation of release of various neurotransmitters in brain. They have been implicated in diverse potential therapeutic applications such as sleepwake disorders, attention-deficient hyperactivity disorder, epilepsy, cognitive impairment and obesity. This review is an attempt to elucidate the function of H3 receptors and their role in various CNS disorders. Also, it is aimed at collating the information on efforts of various medicinal chemists to synthesize the H3 receptor agonists and antagonists in single article.
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Keywords
Pharmacy, Epilepsy, H3 Receptor Antagonists, H3 Receptors, Obesity