H3PW12O40 catalyzed expeditious synthesis of 3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions

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Date

2006-07

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Elsiever

Abstract

Phosphotungstic acid (0.05 mol%) catalyzed one-pot condensation of aryl aldehydes, urea derivatives and β-diketones under microwave irradiation rapidly affords substituted 3,4-dihydropyrimidin-2(1H)-ones in excellent yields and high purity. The low cost catalyst has exhibited remarkable reactivity and reusability.

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Chemistry, Phosphotungstic acid, Solvent-free synthesis, 3,4-Dihydropyrimidin-2(1H)-ones

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