Microwave-assisted formation of peptide-vitamin conjugates
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Date
2012-06-21
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Publisher
Wiley
Abstract
Amino acid and peptide bioconjugates of niacin I, biotin II, α-tocopherol III and cholecalciferol IV are prepared in good to satisfactory yields by using microwave assistance. In addition, a new benzotriazole-activated biotin intermediate is synthesized, which may serve as an advantageous alternative biotinylation reagent.
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Keywords
Chemistry, Microwave-assisted, Peptide–Vitamin