Histone Acetylation Regulates Natriuretic Peptides and Neprilysin Gene Expressions in Diabetic Cardiomyopathy and Nephropathy
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Date
2019
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Publisher
Bentham Science
Abstract
Natriuretic peptide system (NPS) alterations are involved in pathogenesis of diabetic cardiomyopathy (DCM) and nephropathy (DN), however its epigenetic regulation is still unclear. Interestingly, histone acetylation epigenetically regulates neprilysin expression in Alzheimer's disease.
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Keywords
Pharmacy, Diabetic nephropathy, Cardiomyopathy, PCAF/CBP, Histone acetylation, Neprilysin, Diabetic cardiomyopathy