Antidepressant & anxiolytic activities of N-(pyridin-3-yl) quinoxalin-2-carboxamide: A novel serotonin type 3 receptor antagonist in behavioural animal models
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Date
2016
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Publisher
IJMR
Abstract
Alteration in the serotonin leads to the psychological illness, such as depression, anxiety, schizophrenia, eating disorders, obsessive-compulsive disorder, panic disorders and migraines. The objective of the current study was to investigate the antidepressant and anxiolytic activities of N-(pyridin-3-yl) quinoxalin-2-carboxamide (QCF-21), a novel 5-HT3 receptor antagonist in preclinical models of depression and anxiety.
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Keywords
Pharmacy, Anxiety, Behavioural tests, Depression, N-(pyridin-3-yl) quinoxalin-2-carboxamide, Novel 5-HT3 antagonist, Serotonin system