Development and Validation of a Simple High-Performance Liquid Chromatography Method for Estimation of Felodipine in Rabbit Plasma: Application to Pharmacokinetic Study

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dc.contributor.authorPandey, Murali Monohar
dc.date.accessioned2024-01-12T06:47:29Z
dc.date.available2024-01-12T06:47:29Z
dc.date.issued2017
dc.description.abstractA new, simple, specific and sensitive reverse-phase liquid chromatographic method was developed and validated for the estimation of felodipine (FDP) in rabbit plasma using fluorescence detector. Materials and Methods: Plasma standard were prepared using a simple and one-step protein precipitation method and 50 μ l of the standard solutions were injected into the column. The method was found to be linear in the concentration range of 10–1000 ng/ml. The developed bioanalytical method was validated as per standard guidelines. Validation study results demonstrated accuracy, precision, sensitivity and selectivity of the proposed method.en_US
dc.identifier.urihttps://www.eurekaselect.com/article/77973
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13838
dc.language.isoenen_US
dc.publisherBentham Scienceen_US
dc.subjectPharmacyen_US
dc.subjectFelodipineen_US
dc.subjectFluorescence detectoren_US
dc.subjectHigh-performance liquid chromatographyen_US
dc.subjectRabbit plasmaen_US
dc.subjectPharmacokinetic studyen_US
dc.subjectOral tableten_US
dc.titleDevelopment and Validation of a Simple High-Performance Liquid Chromatography Method for Estimation of Felodipine in Rabbit Plasma: Application to Pharmacokinetic Studyen_US
dc.typeArticleen_US

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