TEMPO-Mediated Cross-Dehydrogenative Coupling of Indoles and Imidazo[1,2-a]pyridines with Fluorinated Alcohols
| dc.contributor.author | Kumar, Anil | |
| dc.date.accessioned | 2021-10-14T13:09:24Z | |
| dc.date.available | 2021-10-14T13:09:24Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | A simple and highly efficient metal-free method has been developed for hydroxyfluoroalkylation of indoles and imidazo[1,2-a]pyridines via TEMPO-mediated C(sp3)–H and C(sp2)–H bond cross-dehydrogenative coupling of fluorinated alcohols and indoles. The protocol showed broad substrate scope, afforded good yields of hydroxyfluoroalkylated products, and was amenable for scale-up. Mechanistic investigation indicated involvement of the radical pathway. | en_US |
| dc.identifier.uri | https://pubs.acs.org/doi/abs/10.1021/acs.orglett.1c00031 | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2806 | |
| dc.language.iso | en | en_US |
| dc.publisher | ACS | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Functionalization | en_US |
| dc.subject | Indoles | en_US |
| dc.subject | Chemical reactions | en_US |
| dc.title | TEMPO-Mediated Cross-Dehydrogenative Coupling of Indoles and Imidazo[1,2-a]pyridines with Fluorinated Alcohols | en_US |
| dc.type | Article | en_US |
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